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#GradHacks: A guide to reading research papers
Reading scientific research papers can be a tricky task. It is important to ensure you not only understand the research, but to read it critically and evaluate its reliability. Here is some advice to help you efficiently read, understand and critically evaluate scientific research articles.
The sections
Most research papers follow a similar structure and contain the following sections; abstract, introduction, methods, results, discussion and conclusion. Some articles will contain all of these sections and others will contain some of them.
This provides a high-level summary of what was researched and what the findings were.
Introduction
The introduction gives context to the research by giving information about the field and previous related research that led to this paper. It explains the purpose of the research, what is already known about the topic, the hypotheses that are being tested and how the study will help improve current understanding of the topic. It often includes brief descriptions of key phrases or concepts. Sometimes the introduction includes information about how the research will improve current understanding. However, this is often saved for the discussion and/or conclusion.
Explains how the data was collected and analysed, including how the experiments were set up and what sample, equipment and techniques were used. The statistical techniques are also explained here.
Presents the findings of the research, without bias or interpretation.
The discussion summarises the results. Here, the results are interpreted and their significance is explained. It refers back to the introduction and explains how the study answered the research question(s).
Summarises the key points and findings of the research, the significance of the findings to the field and what the authors believe should be researched in the future based on their findings.
1. Pay attention to the title
The title should tell you the main purpose of the paper. It is also good to look at the authors and their affiliations, which could be important for various reasons, including: for future reference, future employment, for guidance and for checking if the research is reliable.
2. Read critically
When reading a research article, don’t assume that the authors are correct. Instead, keep asking questions along the way, such as ‘is this the right way to answer this question?’, ‘did they do the right statistical analysis?’ and ‘why did they come to that conclusion?’. Taking sample size and statistical significance into consideration is important too.
3. Make notes as you go
Make notes in whatever way suits you best. It can be helpful to print the paper and make notes on it. Alternatively, a greener option is to make notes digitally.
5 tools to help you go paperless
4. read it multiple times.
Research papers contain so much information that it will require you to read it many times before you can fully understand it. Get an understanding of the general purpose of the research and the overall results first, then delve into the finer details once you already have a basic understanding.
5. Read references
Reading some of the references will help you gain background knowledge about the field of research and an understanding of what has been investigated previously.
6. Discuss the paper with someone else
Discussing the paper with someone from your lab or a different lab will show how much you understood and whether you could get more information from it if you read it again. It also helps to reinforce your memory and consolidate what you have learnt.
Steps for reading a paper
1. check the publish date.
Knowing when the research was published helps you have an understanding of whether these are the most recent findings and how likely it is that further studies have taken place since.
2. Skim all of the sections of the paper
Make notes as you do this and look up the meanings of any words you aren’t sure of. A handy tip is to use ctrl F on the keyboard to search for the first time an acronym is mentioned if you come across it later on in a paper, as this is where it will be defined.
3. Read the introduction
Read this in detail to gain some background information on the topic, including what researchers have previously done in this area and why the researchers decided to do this study. Spend longer on this if you are unfamiliar with the topic.
Also, read some of the references included in the introduction if you want to know more.
4. Identify how this paper fits in with the field
What’s the big question that the field is trying to solve? This will help you to understand the impact of the work and why it was done.
5. Read the discussion
This section will give you an understanding of the findings of the paper. You may find it helpful to write notes on the main findings and write down any questions you have, so you can find out the answers when you read the rest of the paper.
6. Read the abstract
To get an overview of the paper. The abstract usually summarises the overall reasons for conducting the study, how the topic was investigated, major findings and a summary of the interpretations/conclusion of these findings. This is a good way to get a summary of the study before reading about it in more detail.
7. Look through the results and methods sections
The methods section can often be the most technical part of the paper. You will likely need to go over this section multiple times to be able to fully get to grips with the procedures and the results.
It is important to take into consideration the following factors when reading the results and methods sections:
- Sample size
- Statistical significance
Again, look up any terms you don’t understand and make a note of them.
8. Write a succinct summary of the research
To check your understanding, write a short summary of the research. This will also help if you are going to write about the paper later in an essay, dissertation, thesis or literature review. Use the following questions as prompts:
- What is the research investigating?
- Why did the research investigate this?
- What was found?
- Are the findings unusual or do they support other research in the field?
- What are the implications of the results?
- What experiments could be carried out to answer any further questions?
Do you have any other tips for reading and critically evaluating research papers? Let us know by leaving a comment!
Banner image paper reference:
Seeman, S., Campagnola, L., Davoudian, P., Hoggarth, A., Hage, T., Bosma-Moody, A., Baker, C., Lee, J., Mihalas, S., Teeter, C., Ko, A., Ojemann, J., Gwinn, R., Silbergold, D., Cobbs, C., Phillips, J., Lein, E., Murphy, G., Koch, C., Zeng, H., and Jarky, T. Sparse recurrent excitatory connectivity in the microcircuit of the adult mouse and human cortex. eLife (2018) doi: 10.7554/eLife.37349
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May 9th, 2016
How to read and understand a scientific paper: a guide for non-scientists.
90 comments | 1612 shares
Estimated reading time: 10 minutes

My post, The truth about vaccinations: Your physician knows more than the University of Google sparked a very lively discussion, with comments from several people trying to persuade me (and the other readers) that their paper disproved everything that I’d been saying. While I encourage you to go read the comments and contribute your own, here I want to focus on the much larger issue that this debate raised: what constitutes scientific authority?
It’s not just a fun academic problem. Getting the science wrong has very real consequences. For example, when a community doesn’t vaccinate children because they’re afraid of “toxins” and think that prayer (or diet, exercise, and “clean living”) is enough to prevent infection, outbreaks happen .
“Be skeptical. But when you get proof, accept proof.” –Michael Specter
What constitutes enough proof? Obviously everyone has a different answer to that question. But to form a truly educated opinion on a scientific subject, you need to become familiar with current research in that field. And to do that, you have to read the “primary research literature” (often just called “the literature”). You might have tried to read scientific papers before and been frustrated by the dense, stilted writing and the unfamiliar jargon. I remember feeling this way! Reading and understanding research papers is a skill which every single doctor and scientist has had to learn during graduate school. You can learn it too, but like any skill it takes patience and practice.
I want to help people become more scientifically literate, so I wrote this guide for how a layperson can approach reading and understanding a scientific research paper. It’s appropriate for someone who has no background whatsoever in science or medicine, and based on the assumption that he or she is doing this for the purpose of getting a basic understanding of a paper and deciding whether or not it’s a reputable study.
The type of scientific paper I’m discussing here is referred to as a primary research article . It’s a peer-reviewed report of new research on a specific question (or questions). Another useful type of publication is a review article . Review articles are also peer-reviewed, and don’t present new information, but summarize multiple primary research articles, to give a sense of the consensus, debates, and unanswered questions within a field. (I’m not going to say much more about them here, but be cautious about which review articles you read. Remember that they are only a snapshot of the research at the time they are published. A review article on, say, genome-wide association studies from 2001 is not going to be very informative in 2013. So much research has been done in the intervening years that the field has changed considerably).
Before you begin: some general advice
Reading a scientific paper is a completely different process than reading an article about science in a blog or newspaper. Not only do you read the sections in a different order than they’re presented, but you also have to take notes, read it multiple times, and probably go look up other papers for some of the details. Reading a single paper may take you a very long time at first. Be patient with yourself. The process will go much faster as you gain experience.
Most primary research papers will be divided into the following sections: Abstract, Introduction, Methods, Results, and Conclusions/Interpretations/Discussion. The order will depend on which journal it’s published in. Some journals have additional files (called Supplementary Online Information) which contain important details of the research, but are published online instead of in the article itself (make sure you don’t skip these files).
Before you begin reading, take note of the authors and their institutional affiliations. Some institutions (e.g. University of Texas) are well-respected; others (e.g. the Discovery Institute ) may appear to be legitimate research institutions but are actually agenda-driven. Tip: g oogle “Discovery Institute” to see why you don’t want to use it as a scientific authority on evolutionary theory.
Also take note of the journal in which it’s published. Reputable (biomedical) journals will be indexed by Pubmed . [EDIT: Several people have reminded me that non-biomedical journals won’t be on Pubmed, and they’re absolutely correct! (thanks for catching that, I apologize for being sloppy here). Check out Web of Science for a more complete index of science journals. And please feel free to share other resources in the comments!] Beware of questionable journals .
As you read, write down every single word that you don’t understand. You’re going to have to look them all up (yes, every one. I know it’s a total pain. But you won’t understand the paper if you don’t understand the vocabulary. Scientific words have extremely precise meanings).

Step-by-step instructions for reading a primary research article
1. Begin by reading the introduction, not the abstract.
The abstract is that dense first paragraph at the very beginning of a paper. In fact, that’s often the only part of a paper that many non-scientists read when they’re trying to build a scientific argument. (This is a terrible practice—don’t do it.). When I’m choosing papers to read, I decide what’s relevant to my interests based on a combination of the title and abstract. But when I’ve got a collection of papers assembled for deep reading, I always read the abstract last. I do this because abstracts contain a succinct summary of the entire paper, and I’m concerned about inadvertently becoming biased by the authors’ interpretation of the results.
2. Identify the BIG QUESTION.
Not “What is this paper about”, but “What problem is this entire field trying to solve?”
This helps you focus on why this research is being done. Look closely for evidence of agenda-motivated research.
3. Summarize the background in five sentences or less.
Here are some questions to guide you:
What work has been done before in this field to answer the BIG QUESTION? What are the limitations of that work? What, according to the authors, needs to be done next?
The five sentences part is a little arbitrary, but it forces you to be concise and really think about the context of this research. You need to be able to explain why this research has been done in order to understand it.
4. Identify the SPECIFIC QUESTION(S)
What exactly are the authors trying to answer with their research? There may be multiple questions, or just one. Write them down. If it’s the kind of research that tests one or more null hypotheses, identify it/them.
Not sure what a null hypothesis is? Go read this , then go back to my last post and read one of the papers that I linked to (like this one ) and try to identify the null hypotheses in it. Keep in mind that not every paper will test a null hypothesis.
5. Identify the approach
What are the authors going to do to answer the SPECIFIC QUESTION(S)?
6. Now read the methods section. Draw a diagram for each experiment, showing exactly what the authors did.
I mean literally draw it. Include as much detail as you need to fully understand the work. As an example, here is what I drew to sort out the methods for a paper I read today ( Battaglia et al. 2013: “The first peopling of South America: New evidence from Y-chromosome haplogroup Q” ). This is much less detail than you’d probably need, because it’s a paper in my specialty and I use these methods all the time. But if you were reading this, and didn’t happen to know what “process data with reduced-median method using Network” means, you’d need to look that up.
Image credit: author
You don’t need to understand the methods in enough detail to replicate the experiment—that’s something reviewers have to do—but you’re not ready to move on to the results until you can explain the basics of the methods to someone else.
7. Read the results section. Write one or more paragraphs to summarize the results for each experiment, each figure, and each table. Don’t yet try to decide what the results mean , just write down what they are.
You’ll find that, particularly in good papers, the majority of the results are summarized in the figures and tables. Pay careful attention to them! You may also need to go to the Supplementary Online Information file to find some of the results.
It is at this point where difficulties can arise if statistical tests are employed in the paper and you don’t have enough of a background to understand them. I can’t teach you stats in this post, but here , here , and here are some basic resources to help you. I STRONGLY advise you to become familiar with them.
Things to pay attention to in the results section:
- Any time the words “significant” or “non-significant” are used. These have precise statistical meanings. Read more about this here .
- If there are graphs, do they have error bars on them? For certain types of studies, a lack of confidence intervals is a major red flag.
- The sample size. Has the study been conducted on 10, or 10,000 people? (For some research purposes, a sample size of 10 is sufficient, but for most studies larger is better).
8. Do the results answer the SPECIFIC QUESTION(S)? What do you think they mean?
Don’t move on until you have thought about this. It’s okay to change your mind in light of the authors’ interpretation—in fact you probably will if you’re still a beginner at this kind of analysis—but it’s a really good habit to start forming your own interpretations before you read those of others.
9. Read the conclusion/discussion/Interpretation section.
What do the authors think the results mean? Do you agree with them? Can you come up with any alternative way of interpreting them? Do the authors identify any weaknesses in their own study? Do you see any that the authors missed? (Don’t assume they’re infallible!) What do they propose to do as a next step? Do you agree with that?
10. Now, go back to the beginning and read the abstract.
Does it match what the authors said in the paper? Does it fit with your interpretation of the paper?
11. FINAL STEP: (Don’t neglect doing this) What do other researchers say about this paper?
Who are the (acknowledged or self-proclaimed) experts in this particular field? Do they have criticisms of the study that you haven’t thought of, or do they generally support it?
Here’s a place where I do recommend you use google! But do it last, so you are better prepared to think critically about what other people say.
(12. This step may be optional for you, depending on why you’re reading a particular paper. But for me, it’s critical! I go through the “Literature cited” section to see what other papers the authors cited. This allows me to better identify the important papers in a particular field, see if the authors cited my own papers (KIDDING!….mostly), and find sources of useful ideas or techniques.)
UPDATE: If you would like to see an example of how to read a science paper using this framework, you can find one here .
I gratefully acknowledge Professors José Bonner and Bill Saxton for teaching me how to critically read and analyze scientific papers using this method. I’m honored to have the chance to pass along what they taught me.
I’ve written a shorter version of this guide for teachers to hand out to their classes. If you’d like a PDF, shoot me an email: jenniferraff (at) utexas (dot) edu. For further comments and additional questions on this guide, please see the Comments Section on the original post .
This piece originally appeared on the author’s personal blog and is reposted with permission.
Featured image credit: Scientists in a laboratory of the University of La Rioja by Urcomunicacion (Wikimedia CC BY3.0)
Note: This article gives the views of the authors, and not the position of the LSE Impact blog, nor of the London School of Economics. Please review our Comments Policy if you have any concerns on posting a comment below.
About the Author
Jennifer Raff (Indiana University—dual Ph.D. in genetics and bioanthropology) is an assistant professor in the Department of Anthropology, University of Kansas, director and Principal Investigator of the KU Laboratory of Human Population Genomics, and assistant director of KU’s Laboratory of Biological Anthropology. She is also a research affiliate with the University of Texas anthropological genetics laboratory. She is keenly interested in public outreach and scientific literacy, writing about topics in science and pseudoscience for her blog ( violentmetaphors.com ), the Huffington Post , and for the Social Evolution Forum .

About the author
90 Comments
Very good Indeed.I always Read Abstract First Time always ……Thanks
Great information and guide to reading and understanding scientific paper. However, there are non-scientific student asked to do scientific research and it would be great to actually give an example and you point out the answers to the steps in the sample article or journal cited. Thank you.
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I can summarize it eve further: three stars by a number in a table = good, no stars = bad
within the context of the fact that a very sizable portion of scientific papers are falsified, what does this article mean?
Your “fact” needs explanation and evidence, otherwise it can be considered alternative.
That’s why you don’t skip step 11
I think it would be useful also to point out that, even after diligently pursuing all of these excellent steps, the reader is usually still unable to determine whether the subjects or materials even existed. Unlike with lay media, where most important stories are covered by multiple sources, and where facts are sometimes checkable from primary sources – even by readers – it is rare indeed that a reader can go beyond the words on the page.
Is the fact that you read instructions on how to read a paper not evidence that there is something wrong with the way we write papers?
The issue of scientific literacy is always challenging for my students. But this is the most practical and helpful guide I’ve ever seen on the web, thanks for this. I usually share with my students the following tips already mentioned above: – Learn the vocabulary before reading – Summarize the background in five sentences or less – Identify the BIG QUESTION
But the pieces of advice this guide gives are structured better and easier. I especially love this one: Don’t yet try to decide what the results mean, just write down what they are. Thanks again for writing this piece!
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you left out ask for the data, so you can check for yourself… (ie trust but verify)
an example a psychology paper that surveyed a group of people about conspiracy theories (n=137) and it’s main/only novel finding was that people that believed in conspiracies theories, there was a tendency for people to believe in mutually contradictory conspiracy theories. ie individual could believe that Princess Diana faked her own death, whilst at the same time had been murdered by MI5
The paper, was duly called – Dead and Alive – M Wood et al…
However. after requesting the data. there was not a single individual person that ticked the survey boxes, that simultaneously believed this finding. Not one person.
The problem, most people surveyed did not believe either of those conspiracies, and inappropriate stats method was applied to data, that assumed a non skewed dataset. Thus, not believing in A and not believing in B correlated, but it also gave a ‘result that believing in A, and Believing in B also correlated..
A very dumb paper… Author still hasn’t retracted it yet.
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I love this! Great simmered-down resource for my undergrads- both science and non-science majors. Thanks for sharing!
“Web of Science” link is broken (at least for me) but a useable alternative is webofknowledge.com (same resource, different name).
I think it is important to note that the journal in which a paper is published is no proof as to the rigor of that paper. A listing in PubMed does not guarantee quality; thus, you need to focus on teaching people how to interpret the paper without relying on a simple JTASS approach to initial assessment. This may be a guide, but nothing more. I say this as a former editor of a MEDLINE journal. There can be good papers in bad journals and bad papers in good ones. But you are correct. Key questions are: What is the question? How will we answer the question? What answer did we get? Did we use the right tools to answer the question? What do we think it means? What else could we do? And thus we can train people to watch for sleights of hand, such as shifting primary outcomes, data mining, salami slicing, etc.
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Yikes! This is a lot of work just to read a single paper! It’s almost the same as writing a paper! I understand the logic in why you recommend this, but the average person is going to be willing to spend 20-30 minutes reading and trying to learn. This method calls for multiple hours of effort and I just don’t seem many non-scientist people being willing to do that when they’re more curious than actually invested. I was really hoping this entry was going to make it easier to navigate the foreign and confusing world that these papers represent, and it probably will if someone does this process repeatedly for quite some time…..like a scientist…..but most of us aren’t scientists and don’t have that kind of time to dedicate to something that’s not our work or family.
By tradition, we expect our scientists to report their findings by codifying them in unreadable gobbledygook. Then we write instructions on how to decode that unreadable nonsense!!
We need to encourage papers to be written in everyday language so it is easier for all. Problem solved.
I wholeheartedly agree with Kaveh Bazargan. From personal experience as a non-scientist trying to do this with medical research papers is a very intimidating and isolating experience. Most people don’t have the time spare to even try to learn this skill. It would be great if systematic reviewers who are acknowledged experts in reading and analysing papers could find a way of communicating the important information about individual papers to non-scientists before – or instead of – burying them in systematic reviews and meta-analyses which are even more difficult to understand. Structured plain language summaries of primary research would be very helpful rather than individuals having to teach themselves how to read and understand a scientific paper which is written for other scientists in “unreadable goggledygook”. Many (most?) papers conceal methodogical flaws in the research conduct which are almost impossible to spot without years of scientific training.
I love this! Extraordinary cooled off assets for my students both science and non-science majors. A debt of gratitude is in order for sharing!
Regarding step 11, if you have access to Web of Science I recommend looking up how many citations the paper has (this will also vary depending on the age of the paper) and who cites it, and whether there even any replies to it in the peer-reviewed literature.
Do you literally do this for every paper you read? I’m curious how much time it takes you to go from start to finish on what you would consider a typical paper. How often do you read new articles a week?
This post has the laudable goal of helping nonscientists understand the primary literature, but the recommendations seem even more onerous than they have to be. For example, the idea that one should write down every single word that he/she doesn’t know? That sounds more like a task for a scientist scrutinizing the work of a rival. For a nonscientist, there may be dozens and dozens of unknown words, and chasing down the meaning of each one may cause a serious forest/trees problem. I agree that there’s no substitute for the hard work of digging into a paper, but following the prescribed advice to the letter would be utterly exhausting for almost any lay reader. I base these comments on my experiences as a biology researcher and undergraduate instructor.
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I really like your post and the effort, but much of the problem wouldn’t exist if we, academics, did a better job in writing down the correct conclusions. Researcher degrees of freedom are seldom properly understood and we keep on having the tendency to be overdeterministic about statistics that are not intended as such. Of course we want to communicate in black and white about our tests (significance!) because it is a human tendency to persuade the reader. Most of the research probably is not as inconsistent as it first seems but we forget to report the proper statistics to see so (CI around the ES)
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Thank you very much for sharing a guide that will help me to follow the best standards for writing a scientific paper even I am not a scientist.
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Reading the abstract last is one, not the, way to read a paper. It it biases the naive reader, then they are not reviewing with a level of skepticism required to evaluate science. We put abstracts first because they lay out the problem, overview the sample and design, and tersely describe what they think they discovered. Then, as I read, I have a roadmap in my head of what to look for to determine for myself whether or not they found something noteworthy.
What is the problem? Are hypotheses to be tested likely to illuminate/clarify the problem? Is the sample appropriate for testing and was it sampled without imputing bias? Were measures appropriate and do they have a history of validity? We the analytics applied appropriate for testing at the level of power needed give the sample size? [Here even many scientist are ill-equipped to judge.] After enumerating results, do the authors list weaknesses in their design that might suggest replication is necessary? If not, check for snow – as in snowjob. If significance levelsare low or variables correlate with one another too much, are moderators discussed? [e.g., results hold for males but not females, old vs young, fat vs skinny, etc.). If so, why were data not re-analyzed to control for moderator effects on results?
Lastly, if the word “prove” appears anywhere in the paper, assume it is junk science (like fake news). Research is never ever done to prove anything. Research is only done to find out. Once a preponderance of studies report a similar finding looking at the same problem with different people, measures, designs, and statistical analyses, then you have something like proof; consensus.
Lastly, if you are a conspiracy theory believer, you will disbelieve any scientific study that does not support your word view. Keep this in mind. A few studies that run counter to the prevailing consensus is not PROOF that your conspiracy is correct, and mainstream science is wrong. I do not know a single scientist (and I know thousands globally) who do not consider climate change to be well-evidenced. Similarly, evolutionary theory remains useful – our current understanding of genomic medicine hinges on cellular mutation, which is evolution on a microscopic scale.
This is a very useful set of instructions, but I found the following statement highly amusing: “Before you begin reading, take note of the authors and their institutional affiliations. Some institutions (e.g. University of Texas) are well-respected; others (e.g. the Discovery Institute) may appear to be legitimate research institutions but are actually agenda-driven.”
All research institutions are agenda driven (including my alma mater, the University of Texas), because funding and professional advancement depend on results. Researchers are fallible humans and subject to temptation and error. There is a very big lawsuit pending against Duke University (see below) for falsifying data.
When I read any research (especially medical), I now search for evidence of legal or professional action. So you might add that as #12: “Lawsuits? Retractions?” Caveat lector.
http://science.sciencemag.org/content/353/6303/977.full
http://www.dukechronicle.com/article/2016/09/experts-address-research-fabrication-lawsuit-against-duke-note-litigation-could-be-protracted
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Weird advice, like: ‘I always read the abstract last’ . This is advice for referees, not for general readers. I always read the abstract first.
An abstract can be misleading, but I am often not qualified enough to judge that. Actually, this blog post title and abstract are misleading too: your advice is for referees, not for non-scientists. So you wanted to provide an immersive experience into a misleading piece, well done 😉
First thing, get rid of the word proof. This is a huge error in that even if you have reputable scientists, journals, institutions, etc. that what is published, especially in a single article, is anything resembling a fact. It is merely research findings from one instance and in no way forms a fact. This is the next level of misinterpretation of science, even among those able to comprehend the journal article, that science produces or discovers facts. There is nothing that is factual that we know of.
Several comments:
For the mid-term exam in a graduate class I took in experimental design the professor would select half a dozen articles from the peer reviewed literature, tell her students to pick three and explain what they had done wrong. New articles for every class and she never ran out.
Beware of articles published in inappropriate journals, no matter how respectable (E.g., something about sociology or criminology published in a medical journal). This is a strategy for sneaking agenda driven research past the peer review process by going to a journal whose reviewers are likely to be unfamiliar with the subject while the editors are sympathetic to the agenda.
There is a reason research papers are written in what looks like “scientific gobbledygook” to lay persons. They are not intended for a lay audience and the goal is to be extremely precise with the technical details of what was done and found so other scientists can examine the results and, most important, attempt to replicate them.. There is no way to simplify the language and put it in lay terms without losing the precision required for a scientific study. E.g., a particle physicist may give a lay explanation of an experiment in metaphorical terms of little balls of energy smashing into each other, but their peers are going to want to see the pages and pages of mathematics that really describe what was happening.
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I would add “Check the source of funding for the research.” If paper on the safety of glyphosate is funded by Bayer or Monsanto, or a paper on climactic change is funded by Exxon, read no further.
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Get the dissertation writing service students look for these days with the prime focus being creating a well researched and lively content on any topic.
The non-scientist should pay extra attention towards this article for the non-technical writing and understanding for them.
A lot of a researcher’s work includes perusing research papers, regardless of whether it’s to remain progressive in their field, propel their logical comprehension, survey compositions, or assemble data for a task proposition or concede application. Since logical articles are not the same as different writings, similar to books or daily paper stories, they ought to be perused in an unexpected way.
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Thanks, I’ll use this a lot for my MSc Thesis.
Those are some great tips but please don’t forget that each school has its own requirements to academic papers.
Clarifying your methodology for reading science paper: excellent idea and great information. Thanks a lot!
Thanks for sharing this blog. Its very helpful for me and I bookmarked this for future
Excelente trabajo, original. Lo recomendaré para mis estudiantes de Posgrado. Si no hay problema, me gustaría hacer una traducción al castellano para el uso de mis estudiantes de pregrado de Sociología.
Excellent work,original. I will recommend it for my graduate students. If there is no problem, I would like to make a translation into Spanish for the use of my undergraduate Sociology students.
Hi Luis, all our works are CC licensed so you are more than welcome to make a translation provided you link back to the original source. See here for details: https://creativecommons.org/licenses/by/3.0/deed.en_GB
Great information , it is very helpful thanks for sharing the blog .
Step 1 and 10 is a great idea, but I still think it’s possible to read the abstract with the introduction and still keep an open mind? and shouldn’t they keep their results for the interpretation section? sorry new to reading scientific papers
Step 1 and 10 is a great idea, but I still think it’s possible to read the abstract with the introduction and still keep an open mind? and shouldn’t they keep their results for the interpretation section? sorry new to reading scientific papers
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Thank you for sharing the tips, they were very helpful.
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The article is extremely helpful. Considering that scientific research are not as easy, the tips in the article are great.
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Thank you for posting this. It has really helped a lot, especially for those of us who always read the abstract first haha
Thanks for writing this blog. It is very much informative and at the same time useful for me
Yeah, great advice on how to be objective from someone who openly declares their prejudice in the opening statement.
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Do you in a real sense do this for each paper you read? I’m interested what amount of time it requires for you to go beginning to end on what you would think about an average paper. How frequently do you read new articles seven days?
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That is literally my question too, I see it as quite time consuming to conduct such a lengthy process for all scientific articles we come across especially as one has other responsibilities to give attention too
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There is a reason research papers are written in what looks like “scientific gobbledygook” to lay persons. They are not intended for a lay audience and the goal is to be extremely precise with the technical details of what was done and found so other scientists can examine the results and, most important, attempt o replicate them.
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Thanks for posting this. You are doing a service to the general public and also graduate students by not only posting this but answering all sincere questions. I have a Ph. D. in Zoology and have been a peer-reviewer for at least 12 papers and am first author of three peer-reviewed papers. I have taught statistics in two universities as a contract professor and all of my papers rely on use of statistics. To answer a frequently asked question, yes, personally it can take me a couple of hours or several more to read some papers. This is true for my colleagues as well. Scientific papers are written so as to be as concise as possible and this can make them hard to read. They often also use technical terms which one has to look up. At least biology and statistics. nothing I have read (or written) has been in “goobledygook” or purposely incomprehensible jargon but they do use terms and concepts that are probably unfamiliar to the layman. I think what the author means, by her comment on absstracts can be intepreted as “don’t JUST read the abstract. Be sure to read the introduction. Personally I go to the discussion and conclusion next.
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Infographic: How to read a scientific paper
Mastering this skill can help you excel at research, peer review – and writing your own papers

Much of a scientist’s work involves reading research papers, whether it’s to stay up to date in their field, advance their scientific understanding, review manuscripts, or gather information for a project proposal or grant application. Because scientific articles are different from other texts, like novels or newspaper stories, they should be read differently.
Research papers follow the well-known IMRD format — an abstract followed by the I ntroduction, M ethods, R esults and D iscussion. They have multiple cross references and tables as well as supplementary material, such as data sets, lab protocols and gene sequences. All those characteristics can make them dense and complex. Being able to effectively understanding them is a matter of practice.
You can use ScienceDirect’s recommendations service to find other articles related to the work you’re reading. Once you've registered , the recommendations engine uses an adaptive algorithm to understand your research interests. It can then find related content from our database of more than 3,800 journals and over 37,000 book titles. The more frequently you sign in, the better it gets to know you, and the more relevant the recommendations you'll receive.
Reading a scientific paper should not be done in a linear way (from beginning to end); instead, it should be done strategically and with a critical mindset, questioning your understanding and the findings. Sometimes you will have to go backwards and forwards, take notes and have multiples tabs opened in your browser.
Here are some tips for reading and understanding research papers.
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- LennyRhine. “ How to Read a Scientific Paper ,” Research4Life Training portal
- Valerie Matarese, PhD (Ed). “ Usingstrategic, critical reading of research papers to teach scientific writing ,” Supporting Research Writing: Rolesand challenges in multilingual settings,” Chandos Publishing, Elsevier (2012)
- Allen H. Renear, PhD, and Carole L. Palmer, PhD. " StrategicReading, Ontologies, and the Future of Scientific Publishing ," Science (2009).
- Angel Borja, PhD. “ 11 steps to structuring a science paper editors will take seriously ,” Elsevier Connect (June 24, 2014)
- Mary Purugganan, PhD, and Jan Hewitt, PhD. “ How to Read a Scientific Article ,” Cain Project in Engineering andProfessional Communication, Rice University
- “How to Read and Review a Scientific Journal Article,”Writing Studio, Duke University
- Robert Siegel, PhD. “ ReadingScientific Papers ,” Stanford University
Related resources
- Elsevier Researcher Academy Free e-learning modules developed by global experts; career guidance and advice; research news on our blog.
- Research4Life Training Portal : A platform with free downloadable resources for researchers. The Authorship Skills section contains 10 modules, including how to read and write scientific papers, intellectual property and web bibliography along with hands-on activity workbooks.
- Career Advice portal of Elsevier Connect : Stories include tips for publishing in an international journal, how to succeed in a PhD program, and how to make your mark in the world of science.
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Natalia Rodriguez
Natalia Rodriguez is the Communications Coordinator for Research4Life , a public-private partnership providing access to scientific information to researchers, academics, students, doctors and other professionals in the developing world. Natalia holds a BSc in biology and an MSc in science communication from Delft University of Technology in the Netherlands. Before joining Research4Life, she worked in the Elsevier's Global Communications department in Amsterdam.
Currently based in Bremen, Germany, Natalia also works as a freelance creative for different organizations, finding innovative ways to communicate science and development.
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How to read and understand a scientific paper: a step-by-step guide for non-scientists.
Assistant Professor of Physical Anthropology, University of Kansas, joint Ph.D. in genetics and anthropology

To form a truly educated opinion on a scientific subject, you need to become familiar with current research in that field. And to be able to distinguish between good and bad interpretations of research, you have to be willing and able to read the primary research literature for yourself. Reading and understanding research papers is a skill that every single doctor and scientist has had to learn during graduate school. You can learn it too, but like any skill it takes patience and practice.
Reading a scientific paper is a completely different process from reading an article about science in a blog or newspaper. Not only do you read the sections in a different order than they're presented, but you also have to take notes, read it multiple times, and probably go look up other papers in order to understand some of the details. Reading a single paper may take you a very long time at first, but be patient with yourself. The process will go much faster as you gain experience.
The type of scientific paper I'm discussing here is referred to as a primary research article. It's a peer-reviewed report of new research on a specific question (or questions). Most articles will be divided into the following sections: abstract, introduction, methods, results, and conclusions/interpretations/discussion.
Before you begin reading a paper, take note of the authors and their institutional affiliations. Some institutions ( e.g. , University of Texas) are well-respected; others may appear to be legitimate research institutions but are actually agenda-driven. Also take note of the journal in which it's published. Be cautious of articles from questionable journals , or sites like Natural News , that might resemble peer-reviewed scientific journals but aren't.
Step-by-Step Instructions for Reading a Primary Research Article
1. Begin by reading the introduction, not the abstract.
The abstract is that dense first paragraph at the very beginning of a paper. In fact, that's often the only part of a paper that many non-scientists read when they're trying to build a scientific argument. (This is a terrible practice. Don't do it.) I always read the abstract last, because it contains a succinct summary of the entire paper, and I'm concerned about inadvertently becoming biased by the authors' interpretation of the results.
2. Identify the big question.
Not "What is this paper about?" but "What problem is this entire field trying to solve?" This helps you focus on why this research is being done. Look closely for evidence of agenda-motivated research.
3. Summarize the background in five sentences or less.
What work has been done before in this field to answer the big question? What are the limitations of that work? What, according to the authors, needs to be done next? You need to be able to succinctly explain why this research has been done in order to understand it.
4. Identify the specific question(s).
What exactly are the authors trying to answer with their research? There may be multiple questions, or just one. Write them down. If it's the kind of research that tests one or more null hypotheses , identify it/them.
5. Identify the approach.
What are the authors going to do to answer the specific question(s)?
6. Read the methods section.
Draw a diagram for each experiment, showing exactly what the authors did. Include as much detail as you need to fully understand the work.

7. Read the results section.
Write one or more paragraphs to summarize the results for each experiment, each figure, and each table. Don't yet try to decide what the results mean ; just write down what they are . You'll often find that results are summarized in the figures and tables. Pay careful attention to them! You may also need to go to supplementary online information files to find some of the results. Also pay attention to:
- The words "significant" and "non-significant." These have precise statistical meanings. Read more about this here .
- Graphs. Do they have error bars on them? For certain types of studies, a lack of confidence intervals is a major red flag.
- The sample size. Has the study been conducted on 10 people, or 10,000 people? For some research purposes a sample size of 10 is sufficient, but for most studies larger is better.
8. Determine whether the results answer the specific question(s).
What do you think they mean? Don't move on until you have thought about this. It's OK to change your mind in light of the authors' interpretation -- in fact, you probably will if you're still a beginner at this kind of analysis -- but it's a really good habit to start forming your own interpretations before you read those of others.
9. Read the conclusion/discussion/interpretation section.
What do the authors think the results mean? Do you agree with them? Can you come up with any alternative way of interpreting them? Do the authors identify any weaknesses in their own study? Do you see any that the authors missed? (Don't assume they're infallible!) What do they propose to do as a next step? Do you agree with that?
10. Go back to the beginning and read the abstract.
Does it match what the authors said in the paper? Does it fit with your interpretation of the paper?
11. Find out what other researchers say about the paper.
Who are the (acknowledged or self-proclaimed) experts in this particular field? Do they have criticisms of the study that you haven't thought of, or do they generally support it? Don't neglect to do this! Here's a place where I do recommend you use Google! But do it last, so you are better prepared to think critically about what other people say.
A full-length version of this post originally appeared on the author's personal blog .
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How to Read a Research Paper – A Guide to Setting Research Goals, Finding Papers to Read, and More
If you work in a scientific field, you should try to build a deep and unbiased understanding of that field. This not only educates you in the best possible way but also helps you envision the opportunities in your space.
A research paper is often the culmination of a wide range of deep and authentic practices surrounding a topic. When writing a research paper, the author thinks critically about the problem, performs rigorous research, evaluates their processes and sources, organizes their thoughts, and then writes. These genuinely-executed practices make for a good research paper.
If you’re struggling to build a habit of reading papers (like I am) on a regular basis, I’ve tried to break down the whole process. I've talked to researchers in the field, read a bunch of papers and blogs from distinguished researchers, and jotted down some techniques that you can follow.
Let’s start off by understanding what a research paper is and what it is NOT!
What is a Research Paper?
A research paper is a dense and detailed manuscript that compiles a thorough understanding of a problem or topic. It offers a proposed solution and further research along with the conditions under which it was deduced and carried out, the efficacy of the solution and the research performed, and potential loopholes in the study.
A research paper is written not only to provide an exceptional learning opportunity but also to pave the way for further advancements in the field. These papers help other scholars germinate the thought seed that can either lead to a new world of ideas or an innovative method of solving a longstanding problem.
What Research Papers are NOT
There is a common notion that a research paper is a well-informed summary of a problem or topic written by means of other sources.
But you shouldn't mistake it for a book or an opinionated account of an individual’s interpretation of a particular topic.
Why Should You Read Research Papers?
What I find fascinating about reading a good research paper is that you can draw on a profound study of a topic and engage with the community on a new perspective to understand what can be achieved in and around that topic.
I work at the intersection of instructional design and data science. Learning is part of my day-to-day responsibilities. If the source of my education is flawed or inefficient, I’d fail at my job in the long term. This applies to many other jobs in Science with a special focus on research.
There are three important reasons to read a research paper:
- Knowledge — Understanding the problem from the eyes of someone who has probably spent years solving it and has taken care of all the edge cases that you might not think of at the beginning.
- Exploration — Whether you have a pinpointed agenda or not, there is a very high chance that you will stumble upon an edge case or a shortcoming that is worth following up. With persistent efforts over a considerable amount of time, you can learn to use that knowledge to make a living.
- Research and review — One of the main reasons for writing a research paper is to further the development in the field. Researchers read papers to review them for conferences or to do a literature survey of a new field. For example, Yann LeCun’ s paper on integrating domain constraints into backpropagation set the foundation of modern computer vision back in 1989. After decades of research and development work, we have come so far that we're now perfecting problems like object detection and optimizing autonomous vehicles.
Not only that, with the help of the internet, you can extrapolate all of these reasons or benefits onto multiple business models. It can be an innovative state-of-the-art product, an efficient service model, a content creator, or a dream job where you are solving problems that matter to you.
Goals for Reading a Research Paper — What Should You Read About?
The first thing to do is to figure out your motivation for reading the paper. There are two main scenarios that might lead you to read a paper:
- Scenario 1 — You have a well-defined agenda/goal and you are deeply invested in a particular field. For example, you’re an NLP practitioner and you want to learn how GPT-4 has given us a breakthrough in NLP. This is always a nice scenario to be in as it offers clarity.
- Scenario 2 — You want to keep abreast of the developments in a host of areas, say how a new deep learning architecture has helped us solve a 50-year old biological problem of understanding protein structures. This is often the case for beginners or for people who consume their daily dose of news from research papers (yes, they exist!).
If you’re an inquisitive beginner with no starting point in mind, start with scenario 2. Shortlist a few topics you want to read about until you find an area that you find intriguing. This will eventually lead you to scenario 1.
ML Reproducibility Challenge
In addition to these generic goals, if you need an end goal for your habit-building exercise of reading research papers, you should check out the ML reproducibility challenge.

You’ll find top-class papers from world-class conferences that are worth diving deep into and reproducing the results.
They conduct this challenge twice a year and they have one coming up in Spring 2021. You should study the past three versions of the challenge, and I’ll write a detailed post on what to expect, how to prepare, and so on.
Now you must be wondering – how can you find the right paper to read?
How to Find the Right Paper to Read
In order to get some ideas around this, I reached out to my friend, Anurag Ghosh who is a researcher at Microsoft. Anurag has been working at the crossover of computer vision, machine learning, and systems engineering.

Here are a few of his tips for getting started:
- Always pick an area you're interested in.
- Read a few good books or detailed blog posts on that topic and start diving deep by reading the papers referenced in those resources.
- Look for seminal papers around that topic. These are papers that report a major breakthrough in the field and offer a new method perspective with a huge potential for subsequent research in that field. Check out papers from the morning paper or C VF - test of time award/Helmholtz prize (if you're interested in computer vision).
- Check out books like Computer Vision: Algorithms and Applications by Richard Szeliski and look for the papers referenced there.
- Have and build a sense of community. Find people who share similar interests, and join groups/subreddits/discord channels where such activities are promoted.
In addition to these invaluable tips, there are a number of web applications that I’ve shortlisted that help me narrow my search for the right papers to read:
- r/MachineLearning — there are many researchers, practitioners, and engineers who share their work along with the papers they've found useful in achieving those results.

- Arxiv Sanity Preserver — built by Andrej Karpathy to accelerate research. It is a repository of 142,846 papers from computer science, machine learning, systems, AI, Stats, CV, and so on. It also offers a bunch of filters, powerful search functionality, and a discussion forum to make for a super useful research platform.

- Google Research — the research teams at Google are working on problems that have an impact on our everyday lives. They share their publications for individuals and teams to learn from, contribute to, and expedite research. They also have a Google AI blog that you can check out.

How to Read a Research Paper
After you have stocked your to-read list, then comes the process of reading these papers. Remember that NOT every paper is useful to read and we need a mechanism that can help us quickly screen papers that are worth reading.
To tackle this challenge, you can use this Three-Pass Approach by S. Keshav . This approach proposes that you read the paper in three passes instead of starting from the beginning and diving in deep until the end.
The three pass approach
- The first pass — is a quick scan to capture a high-level view of the paper. Read the title, abstract, and introduction carefully followed by the headings of the sections and subsections and lastly the conclusion. It should take you no more than 5–10 mins to figure out if you want to move to the second pass.
- The second pass — is a more focused read without checking for the technical proofs. You take down all the crucial notes, underline the key points in the margins. Carefully study the figures, diagrams, and illustrations. Review the graphs, mark relevant unread references for further reading. This helps you understand the background of the paper.
- The third pass — reaching this pass denotes that you’ve found a paper that you want to deeply understand or review. The key to the third pass is to reproduce the results of the paper. Check it for all the assumptions and jot down all the variations in your re-implementation and the original results. Make a note of all the ideas for future analysis. It should take 5–6 hours for beginners and 1–2 hours for experienced readers.
Tools and Software to Keep Track of Your Pipeline of Papers
If you’re sincere about reading research papers, your list of papers will soon grow into an overwhelming stack that is hard to keep track of. Fortunately, we have software that can help us set up a mechanism to manage our research.
Here are a bunch of them that you can use:
- Mendeley [not free] — you can add papers directly to your library from your browser, import documents, generate references and citations, collaborate with fellow researchers, and access your library from anywhere. This is mostly used by experienced researchers.

- Zotero [free & open source] — Along the same lines as Mendeley but free of cost. You can make use of all the features but with limited storage space.

- Notion — this is great if you are just starting out and want to use something lightweight with the option to organize your papers, jot down notes, and manage everything in one workspace. It might not stand anywhere in comparison with the above tools but I personally feel comfortable using Notion and I have created this board to keep track of my progress for now that you can duplicate:

⚠️ Symptoms of Reading a Research Paper
Reading a research paper can turn out to be frustrating, challenging, and time-consuming especially when you’re a beginner. You might face the following common symptoms:
- You might start feeling dumb for not understanding a thing a paper says.
- Finding yourself pushing too hard to understand the math behind those proofs.
- Beating your head against the wall to wrap it around the number of acronyms used in the paper. Just kidding, you’ll have to look up those acronyms every now and then.
- Being stuck on one paragraph for more than an hour.
Here’s a complete list of emotions that you might undergo as explained by Adam Ruben in this article .
Key Takeaways
We should be all set to dive right in. Here’s a quick summary of what we have covered here:
- A research paper is an in-depth study that offers an detailed explanation of a topic or problem along with the research process, proofs, explained results, and ideas for future work.
- Read research papers to develop a deep understanding of a topic/problem. Then you can either review papers as part of being a researcher, explore the domain and the kind of problems to build a solution or startup around it, or you can simply read them to keep abreast of the developments in your domain of interest.
- If you’re a beginner, start with exploration to soon find your path to goal-oriented research.
- In order to find good papers to read, you can use websites like arxiv-sanity, google research, and subreddits like r/MachineLearning.
- Reading approach — Use the 3-pass method to find a paper.
- Keep track of your research, notes, developments by using tools like Zotero/Notion.
- This can get overwhelming in no time. Make sure you start off easy and increment your load progressively.
Remember: Art is not a single method or step done over a weekend but a process of accomplishing remarkable results over time.
You can also watch the video on this topic on my YouTube channel :
Feel free to respond to this blog or comment on the video if you have some tips, questions, or thoughts!
If this tutorial was helpful, you should check out my data science and machine learning courses on Wiplane Academy . They are comprehensive yet compact and helps you build a solid foundation of work to showcase.
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How to Read a Scientific Paper

To read a scientific paper effectively, you should focus on the results and ensure that you draw your own conclusions from the data and assess whether this agrees with the authors’ conclusions. You should also check that the methods are appropriate and make sense. Spend time attending journal clubs and reading online peer reviews of articles to help hone your critical analysis skills and make reading papers easier and quicker.
Keeping up with the scientific literature in your field of interest is incredibly important. It keeps you informed about what is happening in your field and helps shape and guide your experimental plans. But do you really know how to read a scientific paper, and can you do it effectively and efficiently?
Let’s face it, in our results-driven world, reading new scientific papers often falls by the wayside because we just don’t have the time! And when you do find some reading time, it’s tempting not to read the entire article and just focus on the abstract and conclusions sections.
But reading a scientific paper properly doesn’t need to take hours of your time. We’ll show you how to read a scientific paper effectively, what you can and can’t skim, and give you a checklist of key points to look for when reading a paper to make sure you get the most out of your time.
Step 1: Read the Title and Abstract
The title and abstract will give you an overview of the paper’s key points. Most importantly, it will indicate if you should continue and read the rest of the paper. The abstract is often able to view before purchasing or downloading an article, so it can save time and money to read this before committing to the full paper.
Checklist: What to Look for in the Abstract
- The type of journal article. Was it a systematic review? Clinical trial? Meta-analysis?
- The aim. What were they trying to do?
- The experimental setup. Was it in vivo or in vitro, or in silico?
- The key results. What did they find?
- The author’s conclusions. What does it mean? How does it impact the wider field?
Step 2: Skip the Introduction
The introduction is mostly background, and if you are already familiar with the literature, you can scan through or skip this as you probably know it all anyway. You can always return to the introduction if you have time after reading the meatier parts of the paper.
Checklist: What to Look for in the Introduction
- Is the cited literature up to date?
- Do the authors cite only review articles or primary research articles?
- Do they miss key papers?
Step 3: Scan the Methods
Don’t get too bogged down in the methods unless you are researching a new product or technique. Unless the paper details a particularly novel method, just scan through. However, don’t completely ignore the methods section, as the methods used will help you determine the validity of the results.
You should aim to match the methods with the results to understand what has been done. This should be done when reviewing the figures rather than reading the methods section in isolation.
A Note about qPCR Data
If the data is qPCR, take the time to look even more carefully at the methods. According to the MIQE guidelines , the authors need to explain the nucleic acid purification method, yields, and purities, which kits they used, how they determined the efficiency of their assays, and how many replicates they did. There are a lot of factors that can influence qPCR data, and if the paper is leaving out some of the information, you can’t make accurate conclusions from the data.
Checklist: What to Look for in the Methods Section
- Are the controls described? Are they appropriate?
- Are the methods the right choice for the aims of the experiment?
- Did they modify commercial kits, and if so, do they explain how?
- Do they cite previous work to explain methods? If so, access and read the original article to ensure what has been done.
- Ensure adherence to relevant guidelines, e.g., MIQE guidelines for qPCR data.
Step 4: Focus on the Figures
If you want to read a scientific paper effectively, the results section is where you should spend most of your time. This is because the results are the meat of the paper, without which the paper has no purpose.
How you “read” the results is important because while the text is good to read, it is just a description of the results by the author. The author may say that the protein expression levels changed significantly, but you need to look at the results and confirm the change really was significant.
While we hope that authors don’t exaggerate their results, it can be easy to manipulate figures to make them seem more astonishing than they are. We’d also hope this sort of thing would be picked up during editorial and peer review, but peer review can be a flawed process !
Don’t forget any supplementary figures and tables. Just because they are supplementary doesn’t mean they aren’t important. Some of the most important (but not exciting) results are often found here.
We’re not advocating you avoid reading the text of the results section; you certainly should. Just don’t take the authors’ word as gospel. The saying “a picture speaks a thousand words” really is true. Your job is to make sure they match what the author is saying.
And as we mentioned above, read the methods alongside the results and match the method to each figure and table, so you are sure what was done.
A Note About Figure Manipulation
Unfortunately, figure manipulation can be a problem in scientific articles, and while the peer-review process should detect instances of inappropriate manipulation, sometimes things are missed.
And what do we mean about inappropriate manipulation? Not all figure and image manipulation is wrong. Sometimes a western blot needs more brightness or contrast to see the results clearly. This is fine if it is applied to the whole image, but not if it is selectively applied to particular areas. Sometimes there is real intent to deceive, with cases of images swapped, cropped, touched up, or repeated.
Graphs are particularly susceptible to image manipulation, with alterations to graphs changing how the data appears and a reader’s interpretation of a graph. Not starting the axis at 0 can make small differences appear bigger, or vice versa if a scale is too large on the axis. So make sure you pay careful attention to graphs and check the axes (yes, that’s the plural of axis) are appropriate (Figure 1). You should also check if graphs have error bars, and if so, what are they, and is that appropriate?

Statistics can scare many biologists, but it’s important to look at the statistical test and determine if the method is appropriate for the data. Also, be wary of blindly following p-values . You may find situations when an author says something is significant because the statistical test shows a significant p-value, but you can see from the data that it doesn’t look significant. Statistics are not infallible and can be fairly easily manipulated .
Checklist: What to Look for When Reviewing Results
- Are there appropriate scales on graphs?
- Do they use valid statistical analysis? Are results really significant?
- Have they used sufficient n numbers?
- Are the controls appropriate? Should additional controls have been used?
- Is the methodology clear and appropriate?
- Have any figures been inappropriately manipulated?
- Check the supplementary results and methods.
Step 5: Tackle the discussion
The discussion is a great place to determine if you’ve understood the results and the overall message of the paper. It is worth spending more time on the discussion than the introduction as it molds the paper’s results into a story and helps you visualize where they fit in with the overall picture. You should again be wary of authors overinflating their work’s importance and use your judgment to determine if their assertions about what they’ve shown match yours.
One good way to summarize the results of a paper and show how they fit with the wider literature is to sketch out the overall conclusions and how it fits with the current landscape. For example, if the article talks about a specific signaling pathway step, sketch out the pathway with the findings from the paper included. This can help to see the bigger picture, highlight, ensure you understand the impact of the paper, and highlight any unanswered questions.
Test Yourself
A useful exercise when learning how to read a scientific paper (when you have the time!) is to black out the abstract, read the paper and then write an abstract. Then compare the paper’s abstract to the one you wrote. This will demonstrate whether or not you are picking up the paper’s most important point and take-home message.
Checklist: What to Look For in the Discussion Section
- Do you agree with the author’s interpretation of their results?
- Do the results fit with the wider literature?
- Are the authors being objective?
- Do the authors comment on relevant literature and discuss discrepancies between their data and the wider literature?
- Are there any unanswered questions?
Step 6: File it Away
Spending a little time filing your read papers away now can save you A LOT of time in the future (e.g., when writing your own papers or thesis). Use a reference management system and ensure that the entry includes:
- the full and correct citation;
- a very brief summary of the article’s key methods and results;
- any comments or concerns you have;
- any appropriate tags.
Ways to Sharpen Your Critical Analysis Skills
While this article should get you off to a good start, like any muscle, your critical analysis skills need regular workouts to get bigger and better. But how can you hone these skills?
Attend Journal Clubs
Your critical thinking skills benefit dramatically from outside input. This is why journal clubs are so valuable. If your department runs a regular journal club, make sure you attend. If they don’t, set one up. Hearing the views of others can help hone your own critical thinking and allow you to see things from other perspectives. For help and advice on preparing and presenting a journal club session, read our ultimate guide to journal clubs .
Read Online Reviews
Whether in the comments section of the article published online, on a preprint server, or on sites such as PubPeer and Retraction Watch , spend time digesting the views of others. But make sure you apply the same critical analysis skill to these comments and reviews.
These sites can be a useful tool to highlight errors or manipulation you may have missed, but taking these reviews and comments at face value is just as problematic as taking the author’s conclusions as truth. What biases might these reviews have that affect their view? Do you agree with what they say and why?
Final Thoughts on How to Read A Scientific Paper
Reading a scientific paper requires a methodical approach and a critical (but not negative) mindset to ensure that you fully understand what the paper shows.
Reading a paper can seem daunting, and it can be time-consuming if you go in unprepared. However, the process is quicker and smoother once you know how to approach a paper, including what you can and can’t skim. If you don’t have enough time, you can still read a paper effectively without reading the entire paper. Figure 2 highlights what sections can be skimmed and which sections need more of your attention.

Another tip for being more productive (and it’s better for the environment) is to read your papers on-screen . It’ll save time scrambling through a stack of papers and manually filing them away.
Do you have any tips on how to read a scientific paper? Let us know in the comments below.
For more tips on keeping track of the scientific literature, head to the Bitesize Bio Managing the Scientific Literature Hub .
Originally published November 20, 2013. Updated and revised September 2022.
Methods can often be important, to judge whether to even trust the results!
The most important is to save all articles that possibly can be interesting in your reference managing system, and classify them with a relevant tag, so that they can be easily found later. Many articles you don’t realize how important they might be until later on. Then you’ll need to find that article you only read the abstract of six months earlier.
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