Journal of Biotechnology
ISSN: 0168-1656
- Check submitted paper
- Track accepted paper
Most Downloaded Articles
The most downloaded articles from Journal of Biotechnology in the last 90 days.
Potential of microalgae as a sustainable feed ingredient for aquaculture
Senthil Nagappan, Probir Das and 7 more Open Access November 2021
Application of next generation sequencing in clinical microbiology and infection prevention
Ruud H. Deurenberg, Erik Bathoorn and 11 more Open Access February 2017
Rapid and highly efficient mammalian cell engineering via Cas9 protein transfection
Xiquan Liang, Jason Potter and 10 more Open Access August 2015
Enhanced CRISPR/Cas9-mediated precise genome editing by improved design and delivery of gRNA, Cas9 nuclease, and donor DNA
Xiquan Liang, Jason Potter and 3 more Open Access January 2017
Bacterial enzymes involved in lignin degradation
Gonzalo de Gonzalo, Dana I. Colpa, Mohamed H.M. Habib, Marco W. Fraaije Open Access October 2016
Polyhydroxyalkanoate bio-production and its rise as biomaterial of the future
Tania Palmeiro-Sánchez, Vincent O’Flaherty, Piet N.L. Lens Open Access March 2022
Impacts of fast production of afucosylated antibodies and Fc mutants in ExpiCHO-S™ for enhancing FcγRIIIa binding and NK cell activation
Xiaotian Zhong, Jennifer Schenk and 24 more Open Access December 2022
In vitro models of medulloblastoma: Choosing the right tool for the job
Delyan P. Ivanov, Beth Coyle, David A. Walker, Anna M. Grabowska Open Access October 2016
Combinatorial optimization of CRISPR/Cas9 expression enables precision genome engineering in the methylotrophic yeast Pichia pastoris
Astrid Weninger, Anna-Maria Hatzl and 3 more Open Access October 2016
Therapeutic glycoprotein production in mammalian cells
Marie-Eve Lalonde, Yves Durocher Open Access June 2017
The use of bacteriophages to biocontrol oral biofilms
Szymon P. Szafrański, Andreas Winkel, Meike Stiesch Open Access May 2017
Biological control of plant pathogens by Bacillus species
Djordje Fira, Ivica Dimkić and 3 more November 2018
Strategies for analyzing bisulfite sequencing data
Katarzyna Wreczycka, Alexander Gosdschan and 4 more Open Access November 2017
Recombinant Protein L: Production, Purification and Characterization of a Universal Binding Ligand
Stefan Kittler, Julian Ebner and 9 more Open Access November 2022
lac operon induction in Escherichia coli: Systematic comparison of IPTG and TMG induction and influence of the transacetylase LacA
Anja Marbach, Katja Bettenbrock January 2012
Towards maximum acceleration of monoclonal antibody development: Leveraging transposase-mediated cell line generation to enable GMP manufacturing within 3 months using a stable pool
Valerie Schmieder, Juergen Fieder and 21 more Open Access April 2022
Small-scale GMP production of plasmid DNA using a simplified and fully disposable production method
Noor A.M. Bakker, Renate de Boer and 6 more Open Access December 2019
Systematic analysis of CRISPR–Cas9 mismatch tolerance reveals low levels of off-target activity
Emily M. Anderson, Amanda Haupt and 9 more Open Access October 2015
Extraction of astaxanthin from microalga Haematococcus pluvialis in red phase by using generally recognized as safe solvents and accelerated extraction
Antonio Molino, Juri Rimauro and 9 more Open Access October 2018
Recent advances in CRISPR/Cas9-mediated knock-ins in mammalian cells
Mehdi Banan January 2020
Advanced genetic strategies for recombinant protein expression in Escherichia coli
Hans Peter Sørensen, Kim Kusk Mortensen January 2005
Advanced PHB fermentation strategies with CO2-derived organic acids
Elodie Vlaeminck, Koen Quataert and 3 more Open Access January 2022
Flashing lights affect the photophysiology and expression of carotenoid and lipid synthesis genes in Nannochloropsis gaditana
Serena Lima, Jep Lokesh and 7 more Open Access December 2022
Environmental analysis of plastic production processes: Comparing petroleum-based polypropylene and polyethylene with biologically-based poly-β-hydroxybutyric acid using life cycle analysis
K.G. Harding, J.S. Dennis, H. von Blottnitz, S.T.L. Harrison May 2007
Bioinformatics for NGS-based metagenomics and the application to biogas research
Sebastian Jünemann, Nils Kleinbölting and 10 more Open Access November 2017
Academia.edu no longer supports Internet Explorer.
To browse Academia.edu and the wider internet faster and more securely, please take a few seconds to upgrade your browser .
Enter the email address you signed up with and we'll email you a reset link.
- We're Hiring!
- Help Center
Biotechnology research, development, applications and management in Zimbabwe: Review
Information on the nature, trend and quality of biotechnology research, development, applications and management in a country is generally needed to improve policy decisions, guide future research and cooperation, civil society and general public knowledge, technology development agencies and to support public sector implementation of biotechnology research. However, there has been to date no comprehensive publication describing overall biotechnology research and development in Zimbabwe. The little information available only cover agricultural biotechnology in particular plant biotechnology. This paper, therefore, offers a profile of Zimbabwe's overall biotechnology research and development covering activities that provide new knowledge, and the application of biotechnological techniques, biosafety and the regulation status of the biotechnology in the country. The aim is to provide an insight and update of the state of biotechnology in Zimbabwe. This paper also aims to highlight the...
Related Papers
Food Research International
EUGENE KARENZI
Norman Mhazo
Adekunbi Adepoju
International Journal of Food Microbiology
Clement Ndengu
Fems Microbiology Letters
Cesar Hernandez
Pr. Roger DJOULDE Darman
This paper aims at valorising an artisanal honey based alcoholic beverage from northern Cameroon (Africa). The studied process production involved most of stage required for production of mead with difference in starter preparation and handling which include a step of drying and smoking. The must preparation also present light difference with the one of wine production as there’s no activator neither extra nutrients added. But a step of preparation of a so called “Mbii dong” is necessary. “Mbii dong” is a mixture of diluted honey with hot pepper or sometime spices. Some of the accessed physicochemical parameters which include pH, total titrable acidity, residual sugar and total polyphenols indicate similarities with that of mead. It also has to highlight the relatively high alcohol (around 15.4±0.6%) content of the beverage. The recorded values of physicochemical components as alcoholic, volatile acidity, polyphenols… may confirm the fact that a part of festivities, “kuri” can be used as medicines.
James Owusu-Kwarteng
Fura is a spontaneously fermented pearl millet product consumed inWest Africa. The yeast species involved in the fermentation were identified by pheno- and genotypic methods to be Candida krusei, Kluyveromyces marxianus, Candida tropicalis, Candida rugosa, Candida fabianii, Candida norvegensis and Trichosporon asahii. C. krusei and K. marxianus were found to be the dominant species. Survival in pH 2.5 or in the presence of bile salts (0.3% (w/v) oxgall) and growth at 37 °C were independently determined as indicators of the survival potential of the isolates during passage through the human gastrointestinal tract. Selected yeast species isolates were assessed for their probiotic potential. All of the examined yeast isolates survived and grewat human gastrointestinal conditions in pH 2.5, 0.3% (w/v) oxgall at 37 °C. The effect on the transepithelial electrical resistance (TEER) across polarized monolayers of intestinal epithelial cells of human (Caco-2) and porcine (IPEC-J2) origin, were determined. The Caco-2 cells and IPEC-J2 cells displayed clearly different relative TEER results. The strains of C. krusei, K. marxianus, C. rugosa and T. asahii were able to increase the relative TEER of Caco-2 monolayers after 48 h. In comparison, the relative TEER of IPEC-J2 monolayers decreased when exposed to the same yeasts, even though T. asahii did not differ significantly from Saccharomyces cerevisiae var. boulardii which is used as a human probiotic. C. tropicalis resulted in the largest relative TEER decrease for both the human and the porcine cell model assays. Hyphal growth was observed for C. albicans and C. tropicalis after 48 h of incubation with polarized Caco-2 monolayers, whereas this was not the case for the remaining yeast species. In the present study new yeast strains with potential probiotic properties have been isolated to be used potentially as starter cultures for fura production.
Bennie Viljoen
Loading Preview
Sorry, preview is currently unavailable. You can download the paper by clicking the button above.
RELATED PAPERS
Mohamed Hegazy
Ashok Pandey
Gift Matope , Tryness Mhone , Petronella Saidi
M. Zwietering , Loveness Nyanga , Henry Gadaga
R. Nout , Eddy J. Smid , Loveness Nyanga , M. Zwietering
Samir Mahgoub , Mahmoud Sitohy
Food Microbiology
Annalisa Serio , A. Paparella , Clemencia Lopez , Maria Martuscelli
Journal of Applied Microbiology
Michael Gänzle , Emanuele Zannini
Djidjoho Hounhouigan , Wilfrid Padonou
Journal of Food Science
David Peris
Judith Narvhus
Laura Chasseriaud , Marina Bely
International Dairy Journal
Hilde Ostlie
Roger Abrahamsen , T. Mutukumira
Ecology of Food and Nutrition
Eddy J. Smid
LWT - Food Science and Technology
Jorge Saraiva
Acetic Acid Bacteria
Giancarlo Ranalli , Giuseppe Lustrato , luigi grazia
African Journal of …
Victor Enujiugha , M. Ukeyima
Rajen Chettri
International Journal of Food Sciences and Nutrition
Wilson Parawira
Plant foods for human nutrition (Dordrecht, Netherlands)
African Journal of Microbiology Research
Carlien Pohl
Food Technology and …
Henry Gadaga
Journal of microbiology, biotechnology and food sciences
Henry Gadaga , Victor Ntuli
Journal of Biology Agriculture and Healthcare
Kenneth Hosea
Global Science Books
Eugénie Kayitesi
Co. SEP , Mu Ukwuru
- We're Hiring!
- Help Center
- Find new research papers in:
- Health Sciences
- Earth Sciences
- Cognitive Science
- Mathematics
- Computer Science
- Academia ©2023
[email protected] of Nebraska - Lincoln
Home > Chemical and Biomolecular Engineering > Research Papers & Publications > Biotechnology
Chemical and Biomolecular Engineering Research and Publications
Papers in biotechnology.
In vitro evaluation of PEGylated mesoporous MgFe2O4 magnetic nanoassemblies (MMNs) for chemo-thermal therapy , Sunil Kumar, Amita Daverey, Niroj Kumar Sahu, and Dhirendra Bahadur
Identification and characterization of calcium and manganese transporting ATPase (PMR1) gene of Pichia pastoris , Michael P. Dux and Mehmet Inan
A Comparative Study of Monoclonal Antibodies (Mabs) Purified from Cell Culture Supernatant on EDTPA-Modified Zirconia Beads and Protein A-Hyper D Support , Anuradha Subramanian, Blanca Martinez, Jill Holm, Peter W. Carr, and Clayton V. McNeff
Use of Modified Chitosan Macrospheres in the Selective Removal of Immunoglobulins , Anuradha Subramanian, Swapan Roy, Carmine Mascoli, and Jennifer Hommerding
Use of a modified zirconia support in the separation of immunoproteins , Anuradha Subramanian and Sabyasachi Sarkar
UV-vis -infrared optical and AFM study of spin-cast chitosan films , W H. Nosal, D. W. Thompson, Sabyasachi Sarkar, Anuradha Subramanian, John A. Woollam, and L Yan
Identification of the Mass transfer mechanisms involved in the transport of human immunoglobulin - G in N,N,N',N' -ethylnediaminetetramenthylenephosphonic acid modified Zirconia , Sabyasachi Sarkar, Perer W. Carr, and Anuradha Subramanian
Modeling of immunoglobulin uptake by N,N,N′,N′-ethylenediaminetetramethylenephosphonic acid-modified zirconia particles under static and dynamic conditions , Sabyasachi Sarkar and Anuradha Subramanian
Chromatographic Purification of MAbs with Non-Affinity Supports , Anuradha Subramanian
The use of confocal laser scanning microscopy to study the transport of biomacromolecules in a macroporous support , Anuradha Subramanian and Jennifer Hommerding
Crosslinked chitosan: Its physical properties and the effects of matrix stiffness on chondrocyte cell morphology and proliferation , Anuradha Subramanian and Hsin-YI Lin
Preparation and evaluation of the electrospun chitosan/PEO fibers for potential applications in cartilage tissue engineering , Anuradha Subramanian, David Vu, Gustavo F. Larsen, and Hsin YIi Lin
Secretion of Recombinant Human fibrinogen by the Murine Mammary Gland , William H. Velander
Nonequilibrium Thermodynamics in Engineering and Science , Y. Demirel and Stanley I. Sandler
Production and purification of a chimeric monoclonal antibody against botulinum neurotoxin serotype A , Mark C. Mowry, Michael Meagher LEAD INVESTIGATOR, Leonard Smith, and Anuradha Subramanian
Causes of Proteolytic Degradation of Secreted Recombinant Proteins Produced in ethylotrophic Yeast Pichia pastoris: Case Study With Recombinant Ovine Interferon-T , Jayanta Sinha, Bradley A. Plantz, Mehmet Inan, and Michael Meagher
Haemophilic Factors Produced by Transgenic Livestock: Abundance that can enable alternative therapies worldwide , Kevin E. Van Cott, Paul E. Monahan, Timothy C. Nichols, and William H. Velander
Transgenic non-human mammals expressing human coagulation factor VIII and von Willebrand factor , Henryk Lubon, William N. Drohan, and William H. Velander
Characterization and optimization of a chromatographic process based on ethylenediamine-N,N,N′,N′-tetra(methylphosphonic) acid-modified zirconia particles , Sabyasachi Sarkar, Peter W. Carr, Clayton V. McNeff, and Anuradha Subramanian
An approach to sequence DNA without tagging , Sanjun Niu and Ravi F. Saraf
Expression of active human factor IX in mammary tissue and of milk non human transgenic mammals , William H. Velander and William N. Drohan
Expression of a heterologous protein C in mammary tissue of transgenic animals using a long whey acidic protein promoter , William H. Velander, Henryk Lubton, William N. Drohan, and Lothar Hennighausen
Immunoaffinity Chomatography , Anuradha Subramanian
Purification of immunoglobulins from Serum Using Thiophilic Cellulose Beads , Anuradha Subramanian
Ranking the Factors Impacting lmmunosorbent Performance , Anuradha Subramanian and William H. Velander
Modeling Pichia pastoris Growth on Methanol and Optimizing the Production of a Recombinant Protein, the Heavy-Chain Fragment C of Botulinum Neurotoxin, Serotype A , Wenhui Zhang, Mark A. Bevins, Bradley A. Plantz, Leonard A. Smith, and Michael M. Meagher
Bovine Follicular Dynamics, Oocyte Recovery,and Development of Oocytes Microinjected with a Green Fluorescent Protein Construct , M S. CHAUHAN, S Nadir, T L. Bailey, A W. Pryor, S P. Butler, D R. Notter, William H. Velander, and F C. Gwazdauskas
A Red-Dot-Blot Protein Assay Technique in the Low Nanogram Range , Tiilin Marcol and Anuradha Subramanian
Bioactivities of a tumour necrosis like factor released by chicken macrophages , Silke Rautenschlein, Anuradha Subramanian, and Jagdev M. Sharma
Bioactivities of a tumour necrosis like factor released by chicken rnacrophages , Silke Rautenschlein, Anuradha Subramanian, and Jagdev M. Sharma
Crossflow Microfiltration of Recombinant Escherichia coli Lysates after High Pressure Homogenization , Stuart M. Bailey and Michael M. Meagher
Effect of Antibody Orientation on Immunosorbent , Anuradha Subramanian and William H. Velander
Affinity Purification of Biologically Active andInactive Forms of Recombinant Human Protein C Produced in Porcine Mammary Gland , Kevin E. Van Cott; Barry Williams Department of Chemical Engineering,Virginia Tech University, Blacksburg, VA 24061, USA; William H. Velander; Francis C. Gwazdauskas; Tim Lee Jerome Holland Laboratory, American Red Cross, Rockville, MD 20855, USA; Henryk Lubon; and William N. Drohan
Expression of a functional human complement inhibitor in a transgenic pig as a model for the prevention of xenogeneic hyperacute organ rejection. , William L. Fodor, Barry L. Williams, Louis A. MArtis, Josaeph A. Madri, Scott A. Rollins, James W. Knight, William H. Velander, and Stephen P. Squinto
Effect of Culture Conditions, Donor Age, and Injection Site on In Vitro Development of DNA Microinjected Porcine Zygotes , M A. Hajdu, J W. Knight, R S. Cansecot, R L. Krisher, William H. Velander, R E. Pearson, and F C. Gwazdauskas
Effects of Time of Deoxyribonucleic Acid Microinjection on Gene Detection and In Vitro Development of Bovine Embryos , A.E T. Sparks, R S. Canseco, C G. Russell, J L. Johnson, H D. Moll, William H. Velander, and Francis C. Gwazdauskas
High-level expression of a heterologous protein in the milk of transgenic swine using the cDNA encoding human protein C , William H. Velander, John L. Johnson, Raymond L. Page, Christopher G. Russell, Anuradha Subramanian, Tracy D. Wilkins, Francis C. Gwazdauskas, Christoph Pittius, and William N. Drohan
High-level expression of a heterologous protein in the milk of transgenic swine using the cDNA encoding human protein C , William H. Velander, John L. Johnson, Raymond L. Page, Chritopher G. Russell, Anuradha Subramanian, Tracy D. Wilkins, Francis C. Gwazdauskas, Christoph Pittus, and William N. Drohan
In Vitro Development of Zygotes from Prepubertal Gilts After Microinjection of DNA , B. L. Williams, J. L. Johnson, A. E.T. Sparks, R. S. Canseco, J. W. Knight, William H. Velander, R. L. Page, W. N. Drohan, J. M. Young, R. E. Pearson, T. D. Wilkins, and F. C. Gwazdauskas
Enzyme- Facilitated Transport and Separation of Organic Acids through Liquid Membranes , David C. Rethwisch, Anuradha Subramanian, Gao Yi, and Jonathan S. Dordick
Conformational Changes in an Epitope Localized to the NH2-terminal Region of Protein C , Carolyn L. Orthener, Rapti D. Madurawe, William H. Velander, William N. Drohan, Frances D. Bettey, and Dudley K. Strickhand
Advanced Search
Search Help
- Notify me via email or RSS
- How to Cite Items From This Repository
- Copyright Information
- Collections
- Disciplines
Author Corner
- Guide to Submitting
- Submit your paper or article
Home | About | FAQ | My Account | Accessibility Statement
Privacy Copyright
- Search by keyword
- Search by citation
Page 1 of 34
Comparison of vector elements and process conditions in transient and stable suspension HEK293 platforms using SARS-CoV-2 receptor binding domain as a model protein
Mammalian cell lines are frequently used as protein expression hosts because of their ability to correctly fold and assemble complex proteins, produce them at high titers, and confer post-translational modific...
- View Full Text
A fully human connective tissue growth factor blocking monoclonal antibody ameliorates experimental rheumatoid arthritis through inhibiting angiogenesis
Connective tissue growth factor (CTGF) plays a pivotal role in the pathogenesis of rheumatoid arthritis (RA) by facilitating angiogenesis and is a promising therapeutic target for RA treatment. Herein, we gene...
Black glucose-releasing silicon elastomer rings for fed-batch operation allow measurement of the oxygen transfer rate from the top and optical signals from the bottom for each well of a microtiter plate
In industrial microbial biotechnology, fed-batch processes are frequently used to avoid undesirable biological phenomena, such as substrate inhibition or overflow metabolism. For targeted process development, ...
In vitro culture of bovine fibroblasts using select serum-free media supplemented with Chlorella vulgaris extract
Standard cell culture practices require the addition of animal-derived serum to culture media to achieve adequate cell growth. Typically, 5–10% by volume of fetal bovine serum (FBS) is used, which accounts for...
Biochemical characterization and insights into the potency of the acidic Aspergillus niger NRC114 purified α-galactosidase in removing raffinose family oligosaccharides from soymilk yogurt
Because humans lack α-galactosidase, foods containing certain oligosaccharides from the raffinose family, such as soybeans and other legumes, may disrupt digestion and cause flatulence.
Production of rhamnolipid biosurfactants in solid-state fermentation: process optimization and characterization studies
Rhamnolipids are a group of the extracellular microbial surface-active molecules produced by certain Pseudomonas species with various environmental and industrial applications. The goal of the present research wa...
Efficient expression of fusion human epidermal growth factor in tobacco chloroplasts
Chloroplast transformation is a robust technology for the expression of recombinant proteins. Various types of pharmaceutical proteins including growth factors have been reported in chloroplasts via chloroplas...
Enhancing docosahexaenoic acid production of Schizochytrium sp. by optimizing fermentation using central composite design
Docosahexaenoic acid (DHA) can improve human and animal health, particularly including anti-inflammatory, antioxidant, anticancer, neurological, and visual functions. Schizochytrium sp. is a marine heterotrophic ...
Rescue of an enterotropic Newcastle disease virus strain ZM10 from cloned cDNA and stable expressing an inserted foreign gene
Newcastle disease virus (NDV) strain ZM10, a typical enterotropic avirulent vaccine strain, has been widely used in China for chickens against Newcastle disease. To elucidate its enterotropic mechanism and dev...
Correction: Identifcation, expression, and purifcation of DNA cytosine 5-methyltransferases with short recognition sequences
The original article was published in BMC Biotechnology 2022 22 :33
Development of a microbial protease for composting swine carcasses, optimization of its production and elucidation of its catalytic hydrolysis mechanism
Dead swine carcass composting is an excellent method for harmless treatment and resource utilization of swine carcass. However, poor biodegradation ability of traditional composting results in poor harmless tr...
Toxic effects of trace phenol/guanidine isothiocyanate (P/GI) on cells cultured nearby in covered 96-well plates
A mixture of phenol and guanidine isothiocyanate (“P/GI”, the principal components of TRIzol™ and similar products) is routinely used to isolate RNA, DNA, and proteins from a single specimen. In time-course ex...
Modeling and optimizing in vitro percentage and speed callus induction of carrot via Multilayer Perceptron-Single point discrete GA and radial basis function
Callus induction is the first step in optimizing plant regeneration. Fit embryogenesis and shooting rely on callus induction. In addition, using artificial intelligence models in combination with an algorithm ...
Identification, expression, and purification of DNA cytosine 5-methyltransferases with short recognition sequences
DNA methyltransferases (MTases) are enzymes that induce methylation, one of the representative epigenetic modifications of DNA, and are also useful tools for analyzing epigenomes. However, regarding DNA cytosi...
The Correction to this article has been published in BMC Biotechnology 2022 22 :37
Preparation of a novel monoclonal antibody against active components of PHA-L from Phaseolus vulgaris and its functional characteristics
Leukocyte phytohemagglutinin (PHA-L), derived from the L4 tetramer of PHA, has been frequently employed as a mitogen to induce T lymphocyte proliferation in vitro. The biological application of PHA-L in cancer...
Identification of a novel fully human anti-toxic shock syndrome toxin (TSST)-1 single-chain variable fragment antibody averting TSST-1-induced mitogenesis and cytokine secretion
Staphylococcal superantigens are virulence factors that help the pathogen escape the immune system and develop an infection. Toxic shock syndrome toxin (TSST)-1 is one of the most studied superantigens whose r...
Gene cloning and molecular characterization of a thermostable chitosanase from Bacillus cereus TY24
An important conceptual advance in health and the environment has been recognized that enzymes play a key role in the green processing industries. Of particular interest, chitosanase is beneficial for recyclin...
Investigation of neomycin biodegradation conditions using ericoid mycorrhizal and white rot fungal species
In the search for methods to biodegrade recalcitrant compounds, the use of saprotrophic fungi and white rot fungi, in particular belonging to the phylum Basidiomycota, has gained interest. This group of fungi ...
Automatic identification of benign pigmented skin lesions from clinical images using deep convolutional neural network
We aimed to develop a computer-aided detection (CAD) system for accurate identification of benign pigmented skin lesions (PSLs) from images captured using a digital camera or a smart phone.
A new method for screening acute/chronic lymphocytic leukemia: dual-label time-resolved fluorescence immunoassay
Lymphocytic leukemia (LL) is a primary malignant tumor of hematopoietic tissue, which seriously affects the health of children and the elderly. The study aims to establish a new detection method for screening ...
Production of surfactant-stable keratinase from Bacillus cereus YQ15 and its application as detergent additive
With the growing concern for the environment, there are trends that bio-utilization of keratinous waste by keratinases could ease the heavy burden of keratinous waste from the poultry processing and leather in...
Efficient gene delivery into the embryonic chicken brain using neuron-specific promoters and in ovo electroporation
The chicken in ovo model is an attractive system to explore underlying mechanisms of neural and brain development, and it is important to develop effective genetic modification techniques that permit analyses ...
Metabolic engineering of energycane to hyperaccumulate lipids in vegetative biomass
The metabolic engineering of high-biomass crops for lipid production in their vegetative biomass has recently been proposed as a strategy to elevate energy density and lipid yields for biodiesel production. En...
940 nm diode laser induced differentiation of human adipose derived stem cells to temporomandibular joint disc cells
Temporomandibular disorder (TMD) refers to a group of disorders that affect temporomandibular joint (TMJ) and its associated muscles with very limited treatment options. Stem cell research is emerging as one o...
Development of a human phage display-derived anti-PD-1 scFv antibody: an attractive tool for immune checkpoint therapy
The PD-1 checkpoint pathway plays a major role in tumor immune evasion and the development of the tumor microenvironment. Clinical studies show that therapeutic antibodies blocking the PD-1 pathway can restore...
Generation of a recombinant antibody for sensitive detection of Pseudomonas aeruginosa
Pseudomonas aeruginosa ( P. aeruginosa ) is a major pathogen that causes nosocomial infections and often exhibits antibiotic resistance. Therefore, the development of an accurate method for detecting P. aeruginosa ...
Oleic acid based experimental evolution of Bacillus megaterium yielding an enhanced P450 BM3 variant
Unlike most other P450 cytochrome monooxygenases, CYP102A1 from Bacillus megaterium (BM3) is both soluble and fused to its redox partner forming a single polypeptide chain. Like other monooxygenases, it can catal...
Generation of genome-edited dogs by somatic cell nuclear transfer
Canine cloning technology based on somatic cell nuclear transfer (SCNT) combined with genome-editing tools such as CRISPR-Cas9 can be used to correct pathogenic mutations in purebred dogs or to generate animal...
rocF affects the production of tetramethylpyrazine in fermented soybeans with Bacillus subtilis BJ3-2
Tetramethylpyrazine (TTMP) is a flavoring additive that significantly contributes to the formation of flavor compounds in soybean-based fermented foods. Over recent years, the application of TTMP in the food i...
Development of an efficient veterinary rabies vaccine production process in the avian suspension cell line AGE1.CR.pIX
Mass vaccination of dogs as important rabies reservoir is proposed to most effectively reduce and eliminate rabies also in humans. However, a minimum coverage of 70% needs to be achieved for control of the dis...
Oil–water partition coefficient preparation and detection in the dihydroartemisinin self-emulsifying drug delivery system
The aim of the present study is to increase the solubility of dihydroartemisinin (DHA) using the self-emulsifying drug delivery system (SEDDS).
αvβ3-targeted sEVs for efficient intracellular delivery of proteins using MFG-E8
Small extracellular vesicles (sEVs) are nanometer-sized membranous particles shed by many types of cells and can transfer a multitude of cargos between cells. Recent studies of sEVs have been focusing on their...
Introduction of loxP sites by electroporation in the mouse genome; a simple approach for conditional allele generation in complex targeting loci
The discovery of the CRISPR-Cas9 system and its applicability in mammalian embryos has revolutionized the way we generate genetically engineered animal models. To date, models harbouring conditional alleles (i...
Method for quantification of porcine type I interferon activity using luminescence, by direct and indirect means
Type I interferons are widely used in research applications and as biotherapeutics. Current assays used to measure interferon concentrations, such as plaque reduction assays and ELISA, are expensive, technical...
A copper switch for inducing CRISPR/Cas9-based transcriptional activation tightly regulates gene expression in Nicotiana benthamiana
CRISPR-based programmable transcriptional activators (PTAs) are used in plants for rewiring gene networks. Better tuning of their activity in a time and dose-dependent manner should allow precise control of ge...
Isolation and identification of a feather degrading Bacillus tropicus strain Gxun-17 from marine environment and its enzyme characteristics
Feathers are the most abundant agricultural waste produced by poultry farms. The accumulation of a large number of feathers not only seriously pollutes the environment but also causes the waste of protein reso...
A simplified Gibson assembly method for site directed mutagenesis by re-use of standard, and entirely complementary, mutagenesis primers
Site-directed mutagenesis (SDM) is a key method in molecular biology; allowing to modify DNA sequences at single base pair resolution. Although many SDM methods have been developed, methods that increase effic...
Efficient extraction and antioxidant activity of polyphenols from Antrodia cinnamomea
Antrodia cinnamomea , a rare medicinal fungus, has been increasingly studied in recent years because of its abundant secondary metabolites which are beneficial to humans. However, there is a lack of research on it...
Development of a CHO cell line for stable production of recombinant antibodies against human MMP9
Human matrix metalloproteinase 9 (hMMP9) is a biomarker in several diseases, including cancer, and the need for developing detectors and inhibitors of hMMP9 is increasing. As an antibody against hMMP9 can be s...
An efficient and specific CRISPR-Cas9 genome editing system targeting soybean phytoene desaturase genes
Genome editing by CRISPR/Cas9 has become a popular approach to induce targeted mutations for crop trait improvement. Soybean ( Glycine max L. Merr.) is an economically important crop worldwide. Although gene editi...
One-step fermentation for producing xylo-oligosaccharides from wheat bran by recombinant Escherichia coli containing an alkaline xylanase
One-step fermentation is a cheap way to produce xylo-oligosaccharides (XOS), where production of xylanases and XOS is integrated into a single process. In spite of cost advantage, one-step fermentation is stil...
Self-limiting fall armyworm: a new approach in development for sustainable crop protection and resistance management
The fall armyworm, Spodoptera frugiperda , is a significant and widespread pest of maize, sorghum, rice, and other economically important crops. Successful management of this caterpillar pest has historically reli...
Biological modification of pentosans in wheat B starch wastewater and preparation of a composite film
Petrochemical resources are becoming increasingly scarce, and petroleum-based plastic materials adversely impact the environment. Thus, replacement of petroleum-based materials with new and effective renewable...
A study on the processing technology for Rhizoma Coptidis
The present study intends to optimize the processing technology for the wine-processing of Rhizoma Coptidis, using alkaloids as indicators.
Tenebrio molitor : possible source of polystyrene-degrading bacteria
The excessive use of polystyrene as a packaging material has resulted in a rise in environmental pollution. Polystyrene waste has continually increased water pollution, soil pollution and the closing of landfi...
Media optimization for SHuffle T7 Escherichia coli expressing SUMO-Lispro proinsulin by response surface methodology
SHuffle is a suitable Escherichia coli ( E. coli ) strain for high yield cytoplasmic soluble expression of disulfide-bonded proteins such as Insulin due to its oxidative cytoplasmic condition and the ability to cor...
Expression, purification and characterisation of a human anti-CDK4 single-chain variable fragment antibody
Cyclin-dependent kinase 4 (CDK4) when hyperactivated drives development and maintenance of most tumour types, thus prompting its use as an essential cancer treatment target and a diagnostic tool. Target-bindin...
Enzymatic degradation is an effective means to reduce aflatoxin contamination in maize
Aflatoxins are carcinogenic compounds produced by certain species of Aspergillus fungi. The consumption of crops contaminated with this toxin cause serious detrimental health effects, including death, in both liv...
Chloroplast genome sequencing based on genome skimming for identification of Eriobotryae Folium
Whole chloroplast genome (cpDNA) sequence is becoming widely used in the phylogenetic studies of plant and species identification, but in most cases the cpDNA were acquired from silica gel dried fresh leaves. ...
Antibacterial effect of cerium oxide nanoparticle against Pseudomonas aeruginosa
Antibiotics have been widely used for the treatment of bacterial infections for decades. However, the rapid emergence of antibiotic-resistant bacteria has created many problems with a heavy burden for the medi...
Important information
Editorial board
For authors
For editorial board members
For reviewers
- Manuscript editing services
- Follow us on Twitter
Annual Journal Metrics
Citation Impact 3.329 - 2-year Impact Factor (2021) 3.476 - 5-year Impact Factor (2021) 0.892 - SNIP (Source Normalized Impact per Paper) 0.657 - SJR (SCImago Journal Rank)
Speed 39 days to first decision for all manuscripts (Median) 64 days to first decision for reviewed manuscripts only (Median)
Usage 1,076,751 Downloads (2021) 300 Altmetric mentions (2021)
- More about our metrics
BMC Biotechnology
ISSN: 1472-6750
- Submission enquiries: [email protected]
- General enquiries: [email protected]
Current Research in Biotechnology
About the journal.
Excellence paves the way Graphical Reviews: A new way to publish your research
Aims & Scope
- Expertise - Editors and Editorial Board bring depth and breadth of expertise and experience to the journal.
- Speed - Submission and peer review is fast, and publication of final manuscripts is instantaneous.
- Discoverability - Articles get high visibility and maximum exposure on an industry-leading platform that reaches a vast global audience.
Current Research in Biotechnology ( CRBIOT ) is a new primary research, gold open access journal from Elsevier. CRBIOT publishes original papers and short communications (including viewpoints and perspectives ) resulting from research in biotechnology and biotech-associated disciplines. Current …
Article Publishing Charge for open access
* This discount is valid for all authors who wish to publish open access and submit their article by 30 June 2023
Editor-in-Chief
Prof. dr. atanas atanasov, phd, dr. habil.
Ludwig Boltzmann Institute for Digital Health and Patient Safety, Wien, Austria
Latest published
Articles in press, most downloaded, most popular, antioxidant capacity and combinatorial antimicrobial effects of nardostachys jatamansi essential oil with conventional antibiotics against some drug resistant bacteria, phenotyping senescent mesenchymal stromal cells using ai image translation, high-sensitivity profiling of glycoproteins from ovarian cancer sera using lectin-affinity and lc-esi-q-tof-ms/ms, antimicrobial peptides with antiviral and anticancer properties and their modification and nanodelivery systems, genetic and metabolic engineering of methanococcus spp, a survey of the biosynthetic potential and specialized metabolites of archaea and understudied bacteria, xylanases from thermophilic archaea: a hidden treasure, high-throughput biointerfaces for direct, label-free, and multiplexed metaplasmonic biosensing, more from current research in biotechnology, announcements, editor spotlight: prof. dr. atanas atanasov, editor collection: impactful research current opinion in biotechnology, special issues and article collections, advanced nanomaterials based biosensors in clinical diagnosis, environmental protection and industrial fermentation, archaea biotechnology, recent advances on bio-based and biodegradable plastics, integration of biological complexity data with artificial intelligence: towards the development of predictive mathematical models, partner journals, current opinion in biotechnology.
Review articles in Current Opinion in Biotechnology are by invitation only. Current Opinion in Biotechnology (COBIOT) publishes authoritative, comprehensive, and systematic reviews. COBIOT helps specialists keep up to date with a clear and readable synthesis on current advances biotechnology. …
Related journals
Copyright © 2023 Published by Elsevier B.V.
IMAGES
VIDEO
COMMENTS
PDF | This article surveys the rise of biotechnology since the closing decades of the twentieth century, examining both scientific developments and.
The paper suggests that by using biotechnology, traditional knowledge holders may obtain economic gain, through innovation and research and development
One of the important tasks of the OECD Committee for Scientific and Technological Policy ... Earlier work, notably the reports by specialist private firms,.
The most downloaded articles from Journal of Biotechnology in the last 90 days. ... for NGS-based metagenomics and the application to biogas research.
The Web of Science Core Collection online database was searched to retrieve biotechnology articles published since 2017. In total, 12,351 publications were
Biotechnology research, development, applications and management in ... This paper also aims to highlight the country's strengths and weaknesses in
Papers in Biotechnology. Chemical and Biomolecular Engineering Research and Publications · Papers in Biotechnology · Follow. index. 2013 2013. PDF.
The Commission's White Paper3 contributes to a necessary debate ... Genetic manipulation and the right to perform certain research activities;.
BMC Biotechnology is an open access, peer-reviewed journal that considers articles on the manipulation of ... The goal of the present research wa.
Read the latest articles of Current Research in Biotechnology at ScienceDirect.com, Elsevier's leading platform of peer-reviewed scholarly literature.